سونیتینیب مالئات 5 میلیگرمی کد PZ0012 ساخت سیگما

ویرایش

89.12.13

 

جهت دریافت کاتالوگ لطفا روی عکس کلیک کنید


Synonym: N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-2-hydroxybutanedioic acid (1:1) salt, SU 011248, SU 11248, SU112248
  Linear Formula: C22H27FN4O2 · C4H6O5
  Molecular Weight: 532.56
  CAS Number: 341031-54-7

Beschreibung

Biochem/physiol ActionsSunitinib malate is a receptor tyrosine kinase inhibitor, which targets VEGF-R1, VEGF-R2, VEGF-R3, PDGF-Rα, PDGF-Rβ, KIT, FLT3, CSF-1R, and RET. Sunitinib malate is an anticancer drug.
Legal InformationSold for research purposes under agreement from Pfizer Inc.

Eigenschaften

assay≥98% (HPLC)
formpowder
solubilityDMSO: >10 mg/mL
storage temp.room temp

Sicherheit

Hazard CodesT
Risk Statements61-2-48/25
Safety Statements53-22-36/37
WGK Germany2

referenceHersey P., et al., Small molecules and targeted therapies in distant metastatic disease. Ann. Oncol. 6, 35-40, (2009)
 Thomposon Coon JS., et al., Stein K., Sunitinib and bevacizumab for first-line treatment of metastatic renal cell carcinoma: a systematic review and indirect comparison of clinical effectiveness. Br. J. Cancer 101, 238-243, (2009)
 Gan HK., et al., Sunitinib in solid tumors. Expert Opin. Investig. Drugs 18, 821-834, (2009)
MerckMerck 14,9000


فروشنده: آزمیران
گارانتی اصالت و سلامت کالا
پشتیبانی ۷ روز هفته ۲۴ ساعته
۲۲۰,۰۰۰ تومان

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